ViroStat has just released a new set of monoclonal antibodies to the NS1 protein of the yellow fever virus. This protein appears early during the infection in the serum of those infected. These antibodies do not cross react with related flaviviruses.
Yellow fever virus, a member of the flaviviruses, is transmitted to humans via infected mosquitos. Infection occurs in tropical areas including Africa and South America. Typical symptoms include chills, fever, nausea and muscle pain, with improvement usually seen in five days. However, fever can return in some and lead to liver damage, as evidenced by yellowing of the skin. Vaccine is available for travellers to endemic areas.
Enzyme-linked immunosorbent assay (ELISA) pairing recommendations can be found on the datasheet which can be downloaded from the website below.
