RECENT FEATURE ARTICLES

Culture Collections:  ensuring reproducibility  in biomedical science

Culture Collections: ensuring reproducibility in biomedical science

Founded in 1920, the National Collection of Type Cultures is the longest-established collection of its type, and serves as a UNESCO Microbial Resource Centre. Here, Ayuen Lual looks at its role and that of the three other important associated collections.
Sepsis and interleukin-6:  detecting a dysregulated  response to infection

Sepsis and interleukin-6: detecting a dysregulated response to infection

Bacterial sepsis is a major cause of neonatal morbidity and mortality, particularly in preterm babies. Can new rapid cytokine tests improve diagnosis over use of C-reactive protein alone and help reduce unnecessary antibiotic use? Here, John Rees provides an overview and update.
Hepcidin: an interesting journey from bench to  bedside and beyond

Hepcidin: an interesting journey from bench to bedside and beyond

The term translational research is used to describe the application of discoveries made in the research laboratory to medical diagnosis and treatment. The ongoing story of the understanding of hepcidin is a good example of this process.
Myeloma, MGUS and  smouldering disease: an update on significance

Myeloma, MGUS and smouldering disease: an update on significance

One of the uses of serum protein electrophoresis is in detecting a monoclonal gammopathy, the presence of which can indicate a range of related conditions associated with immunoglobulin production.
Early disease detection: driving progress through cutting-edge research

Early disease detection: driving progress through cutting-edge research

A new collaboration between the government and the life sciences industry aims to save tens of thousands of lives through pioneering research to detect deadly diseases as early as possible before symptoms appear.
Hepatitis C: a brief look  in the current literature

Hepatitis C: a brief look in the current literature

Hepatitis C was first discovered in the 1980s and known initially as non-A, non-B hepatitis. It was identified properly in 1989, and in 1991 a screening process was developed making it possible to detect hepatitis C virus in blood samples. As a relatively new disease, there remain many aspects of hepatitis C which are yet to be fully understood, as the following selection of research efforts illustrate.
Digital pathology: putting cybersecurity measures top of the agenda

Digital pathology: putting cybersecurity measures top of the agenda

The latest cybersecurity systems designed by Stago aim to support and protect NHS pathology networks and facilitate real-time data retrieval, uploading, monitoring and sharing at any time, and from anywhere, with total security offering piece of mind.
Measles: the importance  of vaccination, disease  monitoring and surveillance

Measles: the importance of vaccination, disease monitoring and surveillance

The recent resurgence this year in a predominantly childhood infection has focused attention once again on the need to encourage vaccination and therefore increase coverage. Here, Sarah Pitt looks at the background to this and provides an update on progress.
A global commitment to  tackle TB, but more  research needed urgently

A global commitment to tackle TB, but more research needed urgently

After decades of neglect, political attention has finally turned to TB. In 2016, the United Nations General Assembly agreed to hold the first ever High-Level Meeting on TB. Recently, heads of state gathered to make new global commitments to combat the disease, as Mark Pointer reports.
Molecular kits using LAMP  technology: fast, easy,  sensitive and specific

Molecular kits using LAMP technology: fast, easy, sensitive and specific

Loop-mediated isothermal amplification was developed at the turn of the 21st century and in the almost two decades since has proved increasingly useful, especially in resource-poor settings.
Statistical quality control:  a look at process design  – the materials involved

Statistical quality control: a look at process design – the materials involved

Stephen Macdonald returns with the second in a series of articles on internal quality control, specifically looking in this issue at process design and the impact of the materials used.
Going overboard with microbiology – women and children first

Going overboard with microbiology – women and children first

The Autumn Symposium of the British Society for Microbial Technology took place at the Merseyside Maritime Museum in Liverpool last October. On behalf of the BSMT, Mark Wilks reports on a comprehensive and stimulating programme.
Supporting accreditation  for new track-based  haematology platform

Supporting accreditation for new track-based haematology platform

Recently, Torbay Hospital saw the first global installation of the HORIBA HELO fully automated haematology system. A collaborative approach to implementation was key to the success of a process that secured UKAS ISO 15189 accreditation.
Bacterial detection for  healthcare: is BSRMA  the start of a new era?

Bacterial detection for healthcare: is BSRMA the start of a new era?

Following development in the military setting, the bacteria-specific rapid metabolic assay could take a step closer to a new era in bacterial detection. Here, Andrew Kemp provides an overview of progress.
Fresh tissue handling  pathway for the 100,000  Genomes Project

Fresh tissue handling pathway for the 100,000 Genomes Project

In order to optimise and standardise the handling of fresh tissue for the 100,000 Genomes Project, four partner trusts of the West Midlands Genomic Medicine Centre have adopted an innovative vacuum-packing solution.
Prion diseases: a brief look  in the current literature

Prion diseases: a brief look in the current literature

Prion diseases or transmissible spongiform encephalopathies are a family of rare progressive neurodegenerative disorders that affect both humans and animals. A recent confirmed case of bovine spongiform encephalopathy in Scotland has brought this devastating group of diseases, that are usually rapidly progressive and always fatal, back into focus.
Serious Hazards of Transfusion scheme: a review of 2017 data

Serious Hazards of Transfusion scheme: a review of 2017 data

Laboratory incidents specialist Hema Mistry summarises the 2017 SHOT Annual Report, and looks at why the same errors continue to occur and how many of them could have been prevented.
Calprotectin and elastase:  update on faecal testing for  gastrointestinal diseases

Calprotectin and elastase: update on faecal testing for gastrointestinal diseases

Screening of faecal samples for blood and microorganisms is commonplace, yet testing that can distinguish irritable from inflammatory bowel conditions, and detect pancreatic exocrine insufficiency. is equally important, as this review illustrates.
Clinical and Laboratory  Haemostasis 2018: a  UK NEQAS BC update

Clinical and Laboratory Haemostasis 2018: a UK NEQAS BC update

Tim Woods collates abstracts that reflect proceedings of the UK NEQAS for Blood Coagulation annual scientific and participants’ two-day meeting, which was held in Sheffield earlier in the year.
Tuberculosis: a view of  bioinformatics, molecular  typing and spoligotyping

Tuberculosis: a view of bioinformatics, molecular typing and spoligotyping

Over the past decade, much research effort has been invested in the genomics and epidemiology of Mycobacterium tuberculosis infection, one of the world’s deadliest diseases. Currently, scientific and political initiatives aim to improve the situation.

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