RECENT FEATURE ARTICLES

Biomedical Science Congress: highlights from laboratory accreditation to virology

Summaries of lectures on the comprehensive IBMS Biomedical Science Congress scientific lecture programme are requested from individual speakers. In this final review, Pathology in Practice selects programme highlights from alphabetically laboratory accreditation to virology.

EasyScreen flavivirus/alphavirus kit applied to a dengue outbreak

Crystal Garae and colleagues report on validation of the EasyScreen Flavivirus/Alphavirus Detection Kit and its application during the 2016–17 outbreak of dengue virus infection across the islands of Vanuatu.

Learning from haematology external quality assessment: case of a ‘split’ HbA2 peak

Laboratory external quality assessment is more than simple participation in an EQA scheme, as the following case study illustrates. Here, Nikki Emodi and colleagues also consider the limitations inherent in methodology.

Implementation of a new storage solution in a busy virology laboratory

Reliable storage and guaranteed traceability of serum samples is paramount in today’s laboratories. With the ever-increasing pressures on time and productivity, this can prove difficult. Here, James Hudson explains the benefits of the NEO Sample Manager over a previous track-based method used in his laboratory.

Using molecular LAMP to curtail the global threat of carbapenem resistance

Molecular specialist Bradley Horn looks at the application of LAMP technology to combat the growing problem of antimicrobial resistance, particularly in Gram-negative bacteria that increasingly demonstrate multidrug resistance.

Mutation of the BAP1 gene in malignant mesothelioma: a diagnostic evaluation

Evaluation of the identification of a genetic mutation and its association with malignant pleural mesothelioma suggests diagnostic utility, as Justine Ellis and colleagues from East Lancashire and MMU explain.

Statistical quality control: further assessment of more-complex QC charting

In this eighth article in the series on internal quality control, Stephen MacDonald continues his review of the various ways that control can be charted. Here, he focuses on more-complex QC charting.

Snail mucus: antimicrobial properties found in common species of mollusc

The search for novel antibiotic agents, and those that exert their antimicrobial effect in different ways, is currently high on the research agenda. Here, Sarah J Pitt and Alan Gunn review an innovative approach using mucus from common molluscs.

Increased workflow efficiency: a benefit of HbA1c testing on the latest chemistry automation

Against the background of an increasing prevalence of diabetes and demand for glycated haemoglobin testing, workers in the north-east of England have reaped the benefit from the introduction of Beckman Coulter’s new HbA1c assay.

Needle core biopsies: ease and efficiency of processing with LUMEA BxChip

Siobhan Fairgreaves introduces an aid to biopsy processing that protects tissue and facilitates production of maximum diagnostic information. Here, she talks to an early adopter of this innovative chip, and hears of the success achieved with trials in Durham.

CBC-O: how haematology systems aid investigation of a raised MCHC

Modern analyser systems provide cutting-edge support to the haematology laboratory, the latest prime example of which is the benefits provided by equipment and algorithms in the investigation of the cause of a raised mean corpuscular haemoglobin concentration.

Human norovirus: a brief look at research in the current literature

With lower temperatures and shorter periods of daylight at this time of year, norovirus, the so-called ‘winter vomiting bug’, is set to revisit the hospital setting, bringing with it cases of vomiting and diarrhoea. The following items of research interest are all available via PubMed as free PMC articles.

Novel POCT transforms transfusion decision-making in the cardiac theatre

The Royal Wolverhampton NHS Trust and Stago UK have collaborated in a joint interventional study to reduce blood transfusion costs while ensuring patient safety for those undergoing cardiac surgery.

The pressure is on! Are you ready for the winter influenza season?

With the approach of winter and its effect on respiratory illness, Simon Parker of Roche Diagnostics looks at the role of point-of-care PCR influenza assays in facilitating significant improvements in clinical decision-making.

Biomedical Science Congress: highlights from cellular pathology to immunology

Summaries of lectures on the comprehensive IBMS Biomedical Science Congress scientific lecture programme are requested from individual speakers. In this first of two reviews, Pathology in Practice selects highlights from alphabetically cellular pathology to immunology.

Women advancing in science: an ongoing tale of inequalities

Why is it such a struggle for women to get to the top in healthcare science? There is no simple answer, of course, and the reasons are multifactorial. Here, Valerie Bevan considers the issues and outlines her experiences.

Digital transformation: making the case for clinical system validation

In light of the pressures of delivering digital transformation at scale, clinical teams need more support and investment to ensure IT systems are safe to use and fit for purpose, as Stephen Seagreen-Bell explains.

Introducing a total sepsis solution at NHS Greater Glasgow and Clyde

A campaign to raise awareness of sepsis in Scotland, combined with the introduction of the latest technology in microbiology, has had a positive impact on the speed of clinical intervention and potential outcomes in the fight against this serious condition, as Janet Young explains.

SHOT 2018 data: human factors and making the LEAP to transfusion safety

SHOT laboratory incident specialist Victoria Tuckley summarises the 2018 Annual Report, and highlights how to create safer transfusion practices, a more satisfactory working environment and improved patient safety.

Biomarkers for sepsis and the role of automated haematology systems

In the fight against sepsis, modern haematology and haemostasis technology can assist laboratories looking to provide an early diagnosis of this devastating condition caused by a dysregulated host response to infection.