RECENT FEATURE ARTICLES

Platelet diagnostics:  combined technology  means improved testing

Platelet diagnostics: combined technology means improved testing

The investigation of platelet disorders is a major area of interest in haematology and haemostasis. The use of a range of Sysmex technology reduces manual intervention, simplifies processes, improves standardisation and benefits patients.
Sample inoculum  preparation: a UK ring  trial of the Inoclic device

Sample inoculum preparation: a UK ring trial of the Inoclic device

Preparation of a correct inoculum is vitally important when performing antibiotic susceptibility testing. The Inoclic sample preparation device is intended to provide a standardised, reproducible inoculum that produces EUCAST-compliant confluent growth. Here, Anne Grayson and Charlotte Duncan present the results of a UK-wide comparative trial.
IBMS Congress under  the microscope: a mix  of practice and theory

IBMS Congress under the microscope: a mix of practice and theory

In September, the biennial Congress will return to the International Convention Centre in Birmingham. While the main focus is on the comprehensive multidisciplinary lecture programme, workshop sessions also provide delegates with an invaluable opportunity to discuss cellular pathology and cytopathology cases with the experts.
IBMS Congress: focusing in on the exhibition seminar programme

IBMS Congress: focusing in on the exhibition seminar programme

In September, the thirteenth in the biennial Congress series will return to the International Convention Centre in Birmingham. The main focus once again is on the very best that biomedical science and commercial colleagues have to offer, a prime example of which may be found in Hall 4.
Chromosome analysis: from karyotyping to microarray analysis

Chromosome analysis: from karyotyping to microarray analysis

Although the introduction of molecular genetics and use of microarray technology in routine practice has largely replaced conventional karyotyping, there remains a place for the latter in 21st-century cytogenetics.
Evolution of capillary electrophoresis: disease diagnosis and monitoring

Evolution of capillary electrophoresis: disease diagnosis and monitoring

The analysis of serum proteins by capillary electrophoresis has been a feature of routine laboratory practice for several decades. Here, Kayleigh Kirk looks at its development, applications and current instrumentation.
Automated algorithm for lupus anticoagulant testing aids challenging diagnoses

Automated algorithm for lupus anticoagulant testing aids challenging diagnoses

A validation study of a lupus anticoagulant testing algorithm, undertaken by Ghent University Hospital in Belgium and presented at a recent symposium, points to increased quality through standardisation and harmonisation.
Point-of-care biomarker testing supports bacterial infection diagnosis

Point-of-care biomarker testing supports bacterial infection diagnosis

Mandy Campbell provides an overview of the value of using CRP with FBC testing at the point of care, with examples of how this application can impact on antibiotic use in paediatric emergency care, in a frailty assessment centre to prevent unnecessary admissions, and its impact on influenza diagnosis.
Bile acids detection: the value of fourth- and fifth-generation tests

Bile acids detection: the value of fourth- and fifth-generation tests

Obstetric cholestasis is a serious complication of pregnancy that can result in an increased risk of premature birth or even stillbirth. It is vital, therefore, that women with the disease are monitored carefully using the latest complete testing package.
Procalcitonin assay trial: part of initiative to reduce exposure to antibiotics

Procalcitonin assay trial: part of initiative to reduce exposure to antibiotics

The trial of a new procalcitonin assay from Beckman Coulter Diagnostics, undertaken in Portsmouth, is part of an initiative to reduce exposure to antimicrobial agents without a negative impact on patient survival.
Evolution is the solution to challenges faced across the pathology landscape

Evolution is the solution to challenges faced across the pathology landscape

Pressure on vital pathology services is mounting as populations age, chronic conditions increase in frequency and services become constrained by staff shortages. Here, Daniel Chapman discusses how to navigate the increasingly challenging diagnostics landscape, and what he and his team are doing to support evolution of pathology services.
Digital transformation of pathology in Leeds: a quartet of positive views

Digital transformation of pathology in Leeds: a quartet of positive views

A major step towards achieving faster and more accurate diagnosis was taken recently when the histopathology service in Leeds announced that it had gone digital, and now scans every slide produced. Here, different perspectives of the transformation are explored.
With the rapid pace of technology, keeping it simple is sometimes best

With the rapid pace of technology, keeping it simple is sometimes best

Lateral-flow assays have become a common feature across the breadth of in vitro diagnostics. While they are designed to offer a simple visual readout, on occasions weak reactions may cause uncertainty. This is where a lateral-flow reader can help, as Charlotte Duncan explains.
Statistical quality control:  defining goals by  measuring performance

Statistical quality control: defining goals by measuring performance

In this fourth article in a series on internal quality control, Stephen MacDonald moves on to define what standard individual assays are expected to achieve, and the impact of the components of total error.
Improving efficiency in blood sciences: a study of temperature monitoring

Improving efficiency in blood sciences: a study of temperature monitoring

When the blood sciences department at Leeds Teaching Hospitals NHS Trust needed an end-to-end temperature monitoring solution, a solution provided by Checkit was just what the doctor ordered.
Human chorionic gonadotropin:  more than a marker of pregnancy

Human chorionic gonadotropin: more than a marker of pregnancy

Human chorionic gonadotropin is the hormone detected in urine by modern-day point-of-care pregnancy tests. It is produced by syncytiotrophoblasts and, to a lesser extent, cytotrophoblasts in the developing placental tissue following implantation of a blastocyst in the endometrial lining of the uterus. However, a quick look through the current literature confirms that increased hCG level is much more than an indicator of developing life.
Statistical quality control:  a look at process design  – setting IQC targets

Statistical quality control: a look at process design – setting IQC targets

In the third in his series of articles on internal quality control, Stephen MacDonald continues his overview of process design with a look at defining process stability, setting target values, and how they should be used.
Are we making progress  in the battle against  antimicrobial resistance?

Are we making progress in the battle against antimicrobial resistance?

Antimicrobial resistance is a topic of which we should all be aware, and be actively seeking strategies to reduce use of antimicrobial drugs. Here, Kate Woodhead discusses how general awareness is not as good as it should be, and looks at Public Health England’s relaunched public awareness campaign with poster materials and leaflets.
Current progress in  developing ‘universal’  red cell products: a review

Current progress in developing ‘universal’ red cell products: a review

The search for a universal blood product stretches back decades. Hear, Malcolm Needs looks at the various approaches used, and some prospects for the future.
IBMS Congress: an ideal opportunity to link  learning to the laboratory

IBMS Congress: an ideal opportunity to link learning to the laboratory

In September, the thirteenth in the biennial Congress series will return to the International Convention Centre in Birmingham. The focus once again is on the very best that biomedical science and commercial colleagues have to offer. With the launch this month of the full programme, Pathology in Practice provides a brief preview of the event.

Upcoming Events

IBMS Biomedical Science Congress

ICC, Birmingham
22-25 September 2019

Lab Innovations

NEC, Birmingham (Hall 12)
30 & 31 October 2019

The genomic and molecular revolution in microbiology: in technology we trust (or do we?).

RAF Museum, Hendon, London
14 May 2020

Clinical and Laboratory Haemostasis 2020

STEM/Atrium Conference Centre, Sheffield Hallam University
3-4 June 2020

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