RECENT FEATURE ARTICLES

Serious Hazards of Transfusion scheme: a review of 2017 data

Serious Hazards of Transfusion scheme: a review of 2017 data

Laboratory incidents specialist Hema Mistry summarises the 2017 SHOT Annual Report, and looks at why the same errors continue to occur and how many of them could have been prevented.
Calprotectin and elastase:  update on faecal testing for  gastrointestinal diseases

Calprotectin and elastase: update on faecal testing for gastrointestinal diseases

Screening of faecal samples for blood and microorganisms is commonplace, yet testing that can distinguish irritable from inflammatory bowel conditions, and detect pancreatic exocrine insufficiency. is equally important, as this review illustrates.
Clinical and Laboratory  Haemostasis 2018: a  UK NEQAS BC update

Clinical and Laboratory Haemostasis 2018: a UK NEQAS BC update

Tim Woods collates abstracts that reflect proceedings of the UK NEQAS for Blood Coagulation annual scientific and participants’ two-day meeting, which was held in Sheffield earlier in the year.
Tuberculosis: a view of  bioinformatics, molecular  typing and spoligotyping

Tuberculosis: a view of bioinformatics, molecular typing and spoligotyping

Over the past decade, much research effort has been invested in the genomics and epidemiology of Mycobacterium tuberculosis infection, one of the world’s deadliest diseases. Currently, scientific and political initiatives aim to improve the situation.
Statistical quality control:  overview of applications  in the clinical laboratory

Statistical quality control: overview of applications in the clinical laboratory

Following the recent publication of his successful articles on measurement uncertainty, Stephen MacDonald returns with the first in a new series looking at internal quality control in laboratory medicine.
Lymphoid leukaemia:  a look at the genetics  of proliferation

Lymphoid leukaemia: a look at the genetics of proliferation

Treatment of acute lymphoblastic leukaemia in children is one of the great success stories of cancer medicine. Genetic analysis continues to have a major role in the fight against this and other lymphoid leukaemias.
Nostalgia or a reality  check for the IVD industry:  a brief history of change

Nostalgia or a reality check for the IVD industry: a brief history of change

As we move through yet more amalgamation, consolidation, change – call it what you will – a time for reflection and prediction is always worthwhile. Here, Mark Reed offers a brief history of change.
Are you ready for primary molecular screening for human papillomavirus?

Are you ready for primary molecular screening for human papillomavirus?

The NHS Cervical Screening Programme is set to replace cytology screening with the molecular HPV test as the primary form of screening. Here we discuss the impact of this change and the role of a trusted partner in this process.
Next-generation IFA  testing: teaching an  old dog new tricks

Next-generation IFA testing: teaching an old dog new tricks

Jake Morrow looks at the current state of autoantibody testing, what impact this has on provision of the service, and what the future holds for this important area of autoimmunity and immunology.
Measles prevention and virus function: a brief look  in the current literature

Measles prevention and virus function: a brief look in the current literature

Figures released by Public Health England indicate that the numbers of laboratory-confirmed cases of measles increased hugely between 2017 (n=274) and the first half of 2018 (n=738). Recently published articles on the subject from around the world suggest that issues related to poor vaccination uptake and also increased immigration and the associated importation of the virus are just two of a number of reasons for this increase in infection.
Rapid diagnostics – time  is relative: a BSMT Annual  Scientific Meeting report

Rapid diagnostics – time is relative: a BSMT Annual Scientific Meeting report

Mark Wilks reports on the Annual Scientific Conference of the British Society for Microbial Technology, held at Public Health England, Colindale, London, earlier this year.
Point-of-care testing in  microbiology: an overview

Point-of-care testing in microbiology: an overview

The application of point-of-care testing has become commonplace across much of diagnostics. Here, Sarah Pitt looks at the situation in microbiology and how this technology can benefit patient care and infection control.
Translational research: designing the route from  bench to bedside

Translational research: designing the route from bench to bedside

David Martin discusses the role of architectural best practice in supporting translational research, to ensure innovations in the laboratory are transposed rapidly into successful improvements in patient outcomes.
Microbe 2018: a brief  preview of scientific and  commercial excellence

Microbe 2018: a brief preview of scientific and commercial excellence

This year’s Microbe symposium, the 17th biennial event in this series, will return to Sheffield in September. Here, Pathology in Practice provides a preview, including the vital commercial element of proceedings.
Cardiac troponins and the diagnosis of heart disease: some articles in the current literature

Cardiac troponins and the diagnosis of heart disease: some articles in the current literature

Cardiac troponin T (cTnT) and troponin I (cTnI) are cardiac regulatory proteins that control the calcium-mediated interaction between actin and myosin. Raised cardiac troponin concentrations are now accepted as the standard biochemical marker for the diagnosis of myocardial infarction.
Optimising Mohs clinic  flow and patient treatment: the vital role of cryotomy

Optimising Mohs clinic flow and patient treatment: the vital role of cryotomy

The University Hospital of Wales, Cardiff, has pioneered Mohs micrographic surgery since 1992, providing optimal patient care and rapid skin cancer treatment. Central to fast treatment time is cryosectioning, which is facilitated by use of the Thermo Scientific Cryostar NX70.
UK NEQAS: coordinating  point-of-care testing

UK NEQAS: coordinating point-of-care testing

Point-of-care testing is vitally important in many areas of 21st-century healthcare, and requires medical laboratory overview to ensure a safe an efficient service. External quality assessment is an important aspect of this assurance, as this report illustrates.
Storage, archiving and  retrieval of bacteria and  fungi: overview and update

Storage, archiving and retrieval of bacteria and fungi: overview and update

Biobanking increases in importance as scientific development and research continues. Here, Mark Reed offers a brief, not on the high street, insight into what is now a complex science.
Serological infectious  diseases: a solution that  meets a gap in the market

Serological infectious diseases: a solution that meets a gap in the market

Jamie Laughlin explores the benefits of a novel, innovative solution for serological infectious diseases testing recently introduced at South West London Pathology, part of St George’s University Hospitals NHS Foundation Trust.
Assay to assess bleeding  risk in haemophilia A and B  patients: a case study

Assay to assess bleeding risk in haemophilia A and B patients: a case study

A coagulation laboratory in Cambridge is part of a pan-European study looking at the in vitro diagnostics potential for automated thrombin generation testing in the routine laboratory setting.

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