RECENT NEWS

Methotrexate and the treatment of rheumatoid arthritis: an update

Methotrexate and the treatment of rheumatoid arthritis: an update

Since the approval of methotrexate (MTX) for the treatment of rheumatoid arthritis (RA) 30 years ago, there have been a number of new findings about this drug. As a result, the mode of action is increasingly better understood, new indications are identified and the relevant aspects of patient adherence are defined. In practice, this leads to continued therapy optimisation, especially with regard to the dose and route of administration, which was emphasised at the recent Medac Symposium.
Meeting, learning and discovering

Meeting, learning and discovering

In May over 1200 scientists, technicians, speakers and exhibitors descended on the East Midlands Conference Centre at the University of Nottingham for the fifth Scientific Laboratory Show and Conference. Organised by Scientific Laboratory Supplies (SLS), the day brought together delegates from across the community, offering opportunities to meet like-minded people, learn new things and discover the very best scientific technology and equipment for the laboratory.
Celebrate art in science with the Image of the Year Award

Celebrate art in science with the Image of the Year Award

The Olympus Image of the Year European Life Science Light Microscopy Award 2018 recognises the very best in life science imaging. Participants can win a CX23 microscope with EP50 WiFi camera and iPad, an OM-D E-M5 Mark II camera, or a PEN E-PL8 camera.
Savings through quick adoption of new diagnostic techniques

Savings through quick adoption of new diagnostic techniques

Research commissioned by Innovate UK and the British In Vitro Diagnostics Association (BIVDA) reveals that the NHS could save over £6.9 billion in five years through the quick adoption of new diagnostic tests as they come to the market. In turn, these savings could help tackle the annual NHS shortfall, widely expected to reach £20 billion by 2022. Patients would benefit from three new tests, for heart attack, pre-eclampsia and inflammatory bowel disease, by reducing unnecessary procedures and medication while delivering significant NHS savings.
Going Overboard with Microbiology – Women and Children First

Going Overboard with Microbiology – Women and Children First

Following on from a very successful Annual Scientific Meeting held in May, later in the year (Friday 19 October) the British Society for Microbial Technology (BSMT) will hold its Autumn Symposium at the Merseyside Maritime Museum in Liverpool, entitled: Going Overboard with Microbiology – Women and Children First.
Putting it all together: the assessment of uncertainty of measurement

Putting it all together: the assessment of uncertainty of measurement

In the June issue of Pathology in Practice, the seventh article by Stephen MacDonald brings the series on individual aspects of the assessment of uncertainty of measurement to a close. It provides an example of how to set, assess and review measurement uncertainty in any situation in the laboratory.
Strong feelings about point-of-care testing: a personal view

Strong feelings about point-of-care testing: a personal view

For the right reasons and in the right settings, point-of-care testing (POCT) is a great use of technology and could really improve efficiency for the NHS and convenience for the population. The big caveat is that it needs to be done when it is clinically appropriate and not just because technology makes it possible.
Going overboard with microbiology: a BSMT update

Going overboard with microbiology: a BSMT update

The 33rd Annual Scientific Meeting of the British Society for Microbial Technology (BSMT), held recently at PHE, Colindale, proved to be yet another resounding success. The focus of the meeting was Rapid Diagnostics – Time is Relative. Later in the year (Friday 19 October 2018), the BSMT will hold its Autumn Symposium at the Merseyside Maritime Museum in Liverpool, the theme being Going Overboard with Microbiology – Women and Children First.
Humans on a chip – the future for research and drug discovery

Humans on a chip – the future for research and drug discovery

Medicines Discovery Catapult, the Medical Research Council (MRC) Centre for Drug Safety Science (CDSS), based at the University of Liverpool, and the National Centre for the Replacement Refinement & Reduction of Animals in Research (NC3Rs), combined forces recently to bring together experts from the field of organ-on-a-chip technology (OOAC) at the Sensor City in Liverpool.
Putting it all together, building the measurement uncertainty budget

Putting it all together, building the measurement uncertainty budget

The seventh and final article in the Pathology in Practice series by Stephen MacDonald on individual aspects of the assessment of uncertainty of measurement will provide an example of how to set, assess and review measurement uncertainty (MU) in any situation in the laboratory.
Exhibition showcase dedicated to the laboratory

Exhibition showcase dedicated to the laboratory

Lab Innovations returns to the NEC, Birmingham, on 31 October – 1 November 2018. Free-to-attend and supported by some of the UK’s top scientific institutions, Lab Innovations is the nation’s largest gathering of laboratory professionals, with almost a third more attendees in 2017. As well as an exhibition of products and services, visitors can also benefit from learning and business opportunities, with 98% recommending Lab Innovations as a ‘must attend’ event.
Sheffield Coroner’s Office adopts fingertip drug test

Sheffield Coroner’s Office adopts fingertip drug test

Mortuary staff in Sheffield are using a new fingertip-based drug screening system to carry out a simple, non-invasive drug test on the deceased at the city’s Medico-Legal Centre, when pathologists indicate it may be helpful. The test works by analysing sweat deposits that remain on the fingertips after death.
Biomarker test for high-grade prostate cancer could avoid need for biopsy

Biomarker test for high-grade prostate cancer could avoid need for biopsy

ProteoMediX has announced the results from a retrospective study that showed the correlation of its prostate cancer diagnosis test with cancer aggressiveness in patients scheduled for prostate biopsies. The study findings presented at the 2018 European Association of Urology (EAU) Congress in Copenhagen, Denmark, showed that the test has the potential to avoid a large number of biopsies.
Risk of spontaneous preterm birth assessed by point-of-care testing

Risk of spontaneous preterm birth assessed by point-of-care testing

Qiagen has received US regulatory approval for PartoSure, a novel test for assessing the risk of spontaneous preterm birth in patients with symptoms of preterm labour. Approval by the US Food and Drug Administration (FDA) follows successful uptake of the rapid test in more than 35 countries across Europe, the Middle East, Asia and Latin America.
Gene editing to improve red cell transfusion compatibility

Gene editing to improve red cell transfusion compatibility

Synthetic biologists at the University of Bristol have succeeded in generating laboratory-made red blood cells with rare blood group types that could one day be used to help patients who cannot be matched with donor blood.
Organisational changes strengthen push into molecular diagnostics

Organisational changes strengthen push into molecular diagnostics

Oxford Gene Technology (OGT) announced recently that Dr John Anson (pictured) has taken over as CEO from Dr Mike Evans, who has become a non-executive director of OGT’s board. In addition, as part of the company’s increasing focus on diagnostics following its acquisition by Sysmex, OGT has appointed Paul Kenny in a new regulatory position—EVP of Regulatory and Medical Affairs. This new appointment will equip the company to navigate the ever-evolving IVD regulatory landscape.
Diagnostic test to support malaria elimination

Diagnostic test to support malaria elimination

United Kingdom-based test developer Mologic and US-based PATH have entered an agreement to advance a new rapid diagnostic test to support treatment and elimination of Plasmodium vivax, or relapsing, malaria. More than 2.5 billion people worldwide are at risk of infection with P. vivax malaria, mainly in South East Asia and Latin America. P. vivax is especially difficult to eliminate because the parasite can lie dormant in the liver and re-emerge, causing periods of relapsing illness. With each relapse, patients become progressively sicker, and can continue to spread the disease through mosquitoes to other members of the community.
Rapid Diagnostics – Time is Relative

Rapid Diagnostics – Time is Relative

The British Society for Microbial Technology (BSMT) has an excellent programme for its annual scientific conference, to be held on Friday, 18 May at PHE Colindale. The focus will be on Rapid Diagnostics – Time is Relative, and the meeting is relevant for senior biomedical and clinical scientists, other scientists and medical microbiologists.
New diagnostic testing transforms Health Board in South Wales

New diagnostic testing transforms Health Board in South Wales

A year after becoming the first site in the UK to benefit from the latest development in diagnostic testing from Roche Diagnostics, a pathology service in South Wales has seen turnaround times and overall efficiency of its laboratory transformed.
Support for gene and cell therapy applications

Support for gene and cell therapy applications

Gyros Protein Technologies announced recently that Oxford BioMedica has invested in two Gyrolab xPlore systems. This is the first time the Gyrolab technology has been applied within the gene and cell therapy area.

Upcoming Events

Pathology Horizons 2018 Conference

Lough Erne Resort, Co. Fermanagh, Northern Ireland
September 13-15

Microbe 2018

Hilton Hotel, Sheffield
21-23 September 2018

World Congress of the International Federation of Biomedical Laboratory Science (IFBLS)

Palazza dei Congressi of Firenze
22-26 September 2018

Infection Prevention 2018

Scottish Events Campus, Glasgow
30 September - 2 October 2018

Going Overboard with Microbiology - Women and Children First

Merseyside Maritime Museum, Albert Dock, Liverpool
19 October 2018

Latest Issue

Pathology In Practice

Pathology In Practice

Jun 2018

Biomarker testing in suspected pre-eclampsia

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