RECENT NEWS

Meeting of Minds

Meeting of Minds

Congress – in the UK the word means a large, formal meeting of delegates and representatives at which ideas are discussed and information is exchanged.
Lab Innovations returns to NEC Birmingham

Lab Innovations returns to NEC Birmingham

Lab Innovations will return for its sixth consecutive year on 1–2 November 2017 at the NEC, Birmingham. With the largest gathering of laboratory suppliers in the UK, this free-to-attend show has much to offer professionals across a wide range of sectors, from pharmaceuticals to food and drink.
Predicting universal anti-influenza drugs

Predicting universal anti-influenza drugs

University of Hertfordshire researchers have developed a new concept which could lead to the discovery of universal anti-influenza drugs. It is hoped that this new way of including more than 12,000 influenza virus gene sequences will ensure that predicted antivirals are effective against most influenza virus strains. The findings were published recently in the journal Virology.
Re-engineered vancomycin offers hope in fight against antimicrobial resistance

Re-engineered vancomycin offers hope in fight against antimicrobial resistance

Experts have repeatedly warned that medical science is on the cusp of a ‘post-antibiotic era’, where some infections could become untreatable. Now, scientists in the USA have re-engineered a new version of vancomycin in a bid to wipe out one of the world's most threatening microorganisms. The new antibiotic is designed to be ultra-tough and appears to be a thousand times more potent, according to research published in Proceedings of the National Academy of Science USA.
Blood filtration extended to the fight against leukaemia

Blood filtration extended to the fight against leukaemia

MediSieve, the company behind a revolutionary magnetic sieve that filters out malaria-infected cells directly from a patient’s bloodstream, is now developing new methods to combat leukaemia. Following the successful development of its magnetic filter device, which will soon move into clinical trials, MediSieve is now commencing research into the treatment of other conditions using magnetic particles to target specific disease-causing components in blood.
Advances in hybridisation-based targeted sequencing announced

Advances in hybridisation-based targeted sequencing announced

Oxford Gene Technology (OGT) has made several advances in hybridisation-based target enrichment protocols that now enable researchers to prepare samples for sequencing in just one day. Researchers can now access the high-quality results of hybridisation-based targeted sequencing with a speed comparable to that of amplicon-based approaches.
Transforming laboratory services

Transforming laboratory services

Roche Diagnostics has been awarded a seven-year contract by Barts Health NHS Trust to transform its laboratory services across London. The investment, which follows a competitive tender process, will see laboratories at St Bartholomew's Hospital, The Royal London Hospital, Whipps Cross University Hospital and Newham University Hospital upgraded to benefit from the latest in advanced automation.
In EQA and POCT we trust

In EQA and POCT we trust

Diagnostic tests or associated pre-analytical steps are being performed increasing outside the confines of the medical laboratory on a point-of-care (POC) basis. Widespread though such POC testing (POCT) has become, the required governance, quality control and quality assessment is perhaps lagging behind technological application. It will be no surprise, therefore, that accreditation of these widespread services is high on the agenda, and those bodies providing external quality assessment services are sharpening the focus on this near-patient activity.
Rainin pipettes aid research in Spain

Rainin pipettes aid research in Spain

Mettler Toledo’s Rainin pipettes and TerraRack pipette tip racks are helping PhD students in the Department of Biochemistry and Molecular Biomedicine at the University of Barcelona to study metabolic syndrome. Laia Oliva Lorenzo explained: “Our research involves the study of metabolic syndrome at the cellular, tissue and organism level, looking at the cellular metabolism – particularly adipocytes – of rats, and the effects of different diets and obesity. We analyse plasma and tissue samples, and carry out primary adipocyte culture and stromal cell tests.”
Pathology database of tissue images for deep learning

Pathology database of tissue images for deep learning

Royal Philips and LabPON, the first clinical laboratory to move to 100% histopathology digital diagnosis, plans to create a digital database of massive aggregated sets of annotated pathology images and big data, utilising Philips IntelliSite Pathology Solution. The database will provide pathologists with a wealth of clinical information for the development of image analytics algorithms for computational pathology and pathology education, while promoting research and discovery to develop new insights for disease assessment, including cancer.
Cardiac troponin point-of-care testing

Cardiac troponin point-of-care testing

Elkerliek Hospital in The Netherlands and Royal Philips have announced a collaboration to pioneer the use of point-of-care testing (POCT) in the hospital’s dedicated cardiac emergency department. As a key part of the collaboration, Philips’ CE-marked cardiac troponin I (cTnI) blood test for the rapid diagnosis of heart attack, which is based on the company’s Minicare I-20 handheld diagnostics platform, will be used to provide test results within 10 minutes using only a single fingerprick drop of blood.
smartLab: a vision of the future

smartLab: a vision of the future

To design the laboratory of the future you need pioneering and innovative thinkers and developers from research and industry. Scientists and businesses joined together for the smartLAB project to develop a vision of the laboratory of the future. The second edition of this fully functional model laboratory will be on display at LABVOLUTION with BIOTECHNICA, on 16–18 May.
Meeting HBA1c performance criteria

Meeting HBA1c performance criteria

EKF Diagnostics, a global in vitro diagnostics company, has announced that, in a recently published paper (Lenters-Westra E, English, E. Understanding the use of sigma metrics in hemoglobin A1c analysis. Clin Lab Med 2017; 37: 57–71.) its Quo-Test point-of-care (POC) haemoglobin A1c (HbA1c) analyser has been confirmed as meeting International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) performance criteria. Using sigma-metrics data modelling, scientists from the European Reference Laboratory for Glycohemoglobin, demonstrated that Quo-Test easily met IFCC accepted quality targets of >2 sigma at 10% total allowable error (TAE) at 48 mmol/mol HbA1c. This is essential for the effective monitoring of glycaemic control in diabetes patients.
Collaboration to improve identification and measurement of monoclonal proteins

Collaboration to improve identification and measurement of monoclonal proteins

The Binding Site Group has entered a collaboration agreement with Mayo Clinic to develop a novel clinical laboratory test for the identification and accurate measurement of monoclonal proteins present in B-cell diseases. The two organisations want to improve the testing, diagnosis and monitoring of patients with multiple myeloma and related conditions.
Uncertainty of measurement in the clinical laboratory service

Uncertainty of measurement in the clinical laboratory service

Measurement uncertainty in the context of clinical laboratories is inextricably linked to imprecision, and therefore the assessment of this poorly understood factor is an increasing element of the accreditation process. In view of the need to provide some clarity, Pathology in Practice is running a series of articles written by Stephen MacDonald.
Refrigeration technology at the Francis Crick Institute

Refrigeration technology at the Francis Crick Institute

Last year the Francis Crick Institute moved into a brand new building in central London, bringing together 1500 scientists and support staff working collaboratively across disciplines, making it the largest biomedical research facility in Europe under a single roof. As the Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease, it is vital that it has very reliable and secure freezers to enable it to undertake its research effectively and safely.
Hot Topics in Microbiology – Join the Grapevine

Hot Topics in Microbiology – Join the Grapevine

The British Society for Microbial Technology (BSMT) is offering an excellent programme for its annual scientific conference, to be held on Friday, 14 May 2017 in London. This year, the relevance of microbiology to the clinician and life-threatening clinical infections will be explored in Hot Topics in Microbiology – Join the Grapevine.
 Celebrating World Parkinson Day with ‘The Enlightened Mr Parkinson’

Celebrating World Parkinson Day with ‘The Enlightened Mr Parkinson’

World Parkinson’s Disease Day (11 April) is held every year on Parkinson’s birthday to raise awareness of the eponymous disease and the research being done to alleviate the condition. To mark 200 years since James Parkinson first identified the condition, a new biography of this forgotten man will be published.
Supporting personalised treatment for pancreatic cancer

Supporting personalised treatment for pancreatic cancer

A range of clinical trials aimed at developing new treatments for pancreatic cancer will get underway after a £10 million investment from Cancer Research UK. The investment will support the PRECISION Panc project, which aims to develop personalised treatments for pancreatic cancer patients, improving the options and outcomes for a disease in which survival rates have remained stubbornly low.
Bristol breakthrough in the manufacture of red blood cells

Bristol breakthrough in the manufacture of red blood cells

Researchers have generated the first immortalised cell lines that allow more-efficient manufacture of red blood cells. The results, published in Nature Communications (Trakarnsanga K, Griffiths RE, Wilson MC et al. An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells. Nat Commun 2017 Mar 14; 8: 14750. doi: 10.1038/ncomms14750) could, if successfully tested in clinical trials, lead to a safe source of transfusions for people with rare blood types, and in areas of the world where blood supplies are inadequate or unsafe.

Upcoming Events

Microscience Microscopy Congress 2017 (mmc2017)

Manchester
3-6 July 2017

Pathology Horizons CPD conference

Paradise Palms, Cairns, Australia
10th-12th August

UK NEQAS for Blood Coagulation: Providing an Anticoagulant Service

The Principal York Hotel, Station Road, York YO24 1AA
22 September 2017

IBMS Biomedical Science Congress

ICC, Birmingham
24-27 September 2017

UK NEQAS: Coordinating Point-of-Care Testing

Queen Elizabeth II Conference Centre, Broad Sanctuary, Westminster, London SW1 3EE
20 October 2017

Latest Issue

Pathology In Practice

Pathology In Practice

May 2017

Slides for success in tissue adhesion

Register now to apply for regular copies of Pathology In Practice and free access to premium content, as well as our regular newsletters.