FEATURE ARTICLES

The advent of capillary electrophoresis in the routine pathology laboratory brings with it the benefits of quantitative, fully automated analysis of proteins for the diagnosis and monitoring of disease, as Beth Storey explains.

With the recent announcement of Alan TrinderÆs forthcoming retirement as general manager for Olympus Diagnostic Systems, Pathology in Practice has taken the opportunity to talk with Alan and his successor, Steve Swanscott, about their experiences and views of the diagnostics market and of Olympus, past, present and future.

The biochemistry department at KentÆs Medway Maritime Hospital is reaping the rewards of a managed service contract with Siemens Medical Solutions Diagnostics. Here, staff talk about their experiences of a very successful implementation.

CambridgeÆs famous hospital is the site of one of the governmentÆs new biomedical research centres. So, what better location could there be for Beckman Coulter to collaborate with haematology to expand the potential of the laboratoryÆs automation installation?

More than 40 years after being associated with the introduction of single-use laboratory plastics, the Sterilin name continues to set standards for quality and reliability. In conjunction with that of MicroRheologics (Copan Group) in Italy, the name now reflects a major advance in swab technology that provides vastly improved sample collection and release. Rachel Adams explains.

Point-of-care testing is finding increasing application in healthcare, and monitoring patients on anticoagulant therapy is just one example of how this aspect of pathology modernisation is evolving. Here, Robert Powley examines a hand-held coagulometer from Inverness Medical UK.

Growing demand for more information about medical conditions and treatments has now become a reality in modern healthcare. Medical Solutions is at the forefront of breast cancer diagnosis and offers comprehensive test portfolios designed to answer key questions about disease prognosis and treatment options for the patient.

Transport a Victorian laboratory assistant into a modern-day histopathology department and they would feel immediately at home with tissue processing. However, things are moving on at last, and xylene-free processing is one example of changing methodology, as Glyn Woodward explains.

The use of tissue microarray methodologies has increased dramatically over the past decade. Now, the National Cancer Institute and The Netherlands Cancer Institute have become the first research organisations to adopt TMALab II software.

The unmasking, labelling and detection systems that together represent modern-day immunohistochemical technique have been refined over the past quarter of a century. However, Vector continues to produce dividends at the cutting edge of cellular pathology technique, as Ian MacKarill explains.

An Australian study of the ThinPrep Imaging System from Cytyc featured in a recent issue of the British Medical Journal. A synopsis of the findings is summarised below.

With strict new blood bank refrigeration and storage requirements now in force to comply with European regulations, and with MHRA inspections imminent, Barry Hill talks to one company that has a solution to the present concerns.

The management of stock is a crucial factor to smooth running in the laboratory environment. Introduction of the StockTraxx NHS inventory system has enabled Newcastle upon Tyne NHS Foundation TrustÆs biochemistry department to control costs and operate just-in-time ordering.

Although one of the oldest disciplines in pathology, microbiology has experienced little impact from automation. However, the debut of the AccuPAS system may be about to change this perception, as Catherine Balding reports.

In the current NHS climate, trusts are continually looking for ways to reduce their financial exposure. Thus, the management services of a vendor-independent company such as Asteral have great appeal, particularly in the field of laboratory medicine.

The use of latex agglutination methodology is ubiquitous in pathology, having first been described over 50 years ago. Now, advances in technology employed by Pro-Lab Diagnostics mean that visual results are now faster, clearer and more specific.

Concerns in blood transfusion departments about the need to meet the demands of the EU Blood Directive, and other requirements, has led one UK company to develop an innovative standalone information technology solution to address the problem.

The haematology service across two large Sheffield hospitals is supported by a laboratory informatics system from Beckman Coulter. This Yorkshire facility now represents the largest Remisol set-up in Europe and contributes to cutting-edge biomedical science at its best.

Monitoring short-term cell growth in culture and biofermentation assays is notoriously inaccurate and slow using conventional laboratory techniques. However, introduction of the VoluPAC tube has resulted in increased reliability and precision, as Martin Jordan, Matthieu Stettler and Florian Wurm explain.

Currently, antibiotic resistance is a major issue, particularly in the hospital setting, and susceptibility testing plays a vital role in monitoring this problem. OxoidÆs recently introduced simple, precise and easy-to-implement MIC strip system should help.