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Genius in Oklahoma

SyngeneÆs ChemiGenius2 multipurpose imaging system is being used by the University of Oklahoma for a fluorescence imaging application which is part of an important study into the causes of blindness associated with diabetes.

Scientists at the University of Oklahoma College of Medicine are using the ChemiGenius2 in a special way to analyse slides of fluorescently labelled eye tissue. The system is also in use for routine tasks such as checking the quality and size of DNA fragments and determining protein expression by Western blotting. The ultimate goal of this research is to develop natural peptides as new noninvasive therapies to block vascular leakage in the eyes, preventing retinal degeneration and subsequent blindness caused by diseases such as diabetes. Dr Jian-Xing Ma, professor in the Department of Cell Biology, University of Oklahoma College of Medicine commented: ôBefore installing ChemiGenius2 we used Polaroid film to document our research. The new system lets us produce publication-quality images and store them on our desktops. We have to perform a number of diverse imaging tasks and this system offers the most versatility. Also, the software is so simple to use that we can quickly and easily email images back to our desks for analysis with SyngeneÆs GeneTools.ö SyngeneÆs Paula Maia added: ôIt is exciting to see ChemiGenius2 imaging fluorescently stained slides as this is a new application of it. This research shows how a ChemiGenius2 can save time and expense in generating quality images which can be confidently submitted to any regulatory authority.ö

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