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Paraffin-reactive CD19 antibody

Serotec has launched the only commercially available anti-human CD19 (MCA2454) monoclonal antibody suitable for paraffin-reactive immunohistological studies.

CD19 is a 95 kDa member of the immunoglobulin superfamily. It is a characteristic B-cell marker expressed from the early stages of commitment to B-cell lineage, and on all mature B cells. It is absent from plasma cells.

CD19 has been used widely in flow cytometry as a specific marker of B-cell lineage for leukaemias and lymphomas, and this antibody will now make immunohistological assessment of this important lineage marker possible in routinely fixed tissues. MCA2454 is a multi-purpose antibody that also works well in immunoprecipitation, Western blotting and flow cytometry following cell surface permeabilisation.

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