Applied Biosystems has developed a new small RNA expression analysis solution optimised for the SOLiD system, the company’s ultra-high-throughput platform for DNA sequencing and genomic analysis. This solution includes a new multiplexing technology (also known as barcoding) that enables the simultaneous analysis of up to 256 biological samples in a single sequencing run.
In addition to the multiplexing technology, the SOLiD system’s two-base encoding is capable of highly accurate sequencing to yield reliable data for microRNA profiling studies. The two-base encoding chemistry discriminates random or systematic errors from true variants throughout the genome to reveal genetic variants with greater than 99.94% accuracy.
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