Applied Biosystems has developed a sequencing-based molecular tool for the genomic analysis of whole transcriptomes, the vast collection of RNAs transcribed from a genome. This technology, which provides detailed characterisation of expressed protein-encoding genes, identifies many non-coding RNAs and includes sample multiplexing capability, is expected to be available for limited release through an early access programme that will begin in November 2008.
The application of the kit should advance treatment of complex diseases such as diabetes, heart disease and cancer, and accelerate studies in which analysis of differential RNA expression provides insight into the level and mechanism of action of a particular treatment.
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