Histological examination is considered the gold standard for detection, diagnosis and characterisation of many clinical conditions, and producing suitable sections for microscopy examination constitutes one of the primary skills of the histologist.
To promote good ribbon generation, the paraffin block needs to be sufficiently hard to enable sections to be cut, and this achieved by placing the block on ice, cooling the tissue and the wax to a similar consistency.
As an alternative to the use of ice, the Thermo Scientific Cool Cut clamp is a Peltier-cooled specimen clamp that maintains the paraffin block at a suitable temperature for sectioning for a prolonged period. Compatible with all the Thermo Scientific HM range of rotary microtomes, the Thermo Scientific Cool Cut provides the ability to achieve consistent section thickness when cutting individual, step and serial sections, with minimal interruptions.
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