Fluorescence in situ hybridisation probes

Oxford Gene Technology has expanded its range of Cytocell Aquarius fluorescence in situ hybridisation (FISH) probes for pathology. OGT has introduced three new probes, FUS Breakapart and FOXO1 Breakapart, both carrying the CE-IVD label, and TFE3 Breakapart, for research use only. This expansion reinforces OGT’s commitment to providing the most comprehensive and up-to-date range available, facilitating cancer research and diagnosis.

Developed in response to customer need, the genes for both FUS and FOXO1 are both implicated in several debilitating neoplastic diseases. Recurrent rearrangements involving the FUS gene with a number of different partner genes have been reported in various types of neoplastic disease, notably soft tissue sarcomas and acute myeloid leukaemia. Translocations involving the FOXO1 gene are associated with around 80% of cases of alveolar rhabdomyosarcoma.

Commenting on the latest launch of Aquarius FISH probes, Steve Chatters (Senior Product Manager for Pathology at OGT) explained: “These new probes clearly show OGT’s commitment to high-quality FISH probes in the fast-moving field of cancer research; with over 20 new FISH probes released in the last year, Cytocell’s FISH portfolio is second-to-none in both range and quality. We are committed to keeping up with our customers’ expectations by expanding the Cytocell cancer FISH probe range in 2017.”

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