Haemoglobinopathies: screening by capillary electrophoresis

The two major roles of the haemoglobinopathy laboratory are the recognition of clinically important variant haemoglobins and the accurate and precise quantification of haemoglobin A2 for the diagnosis of β-thalassaemia heterozygosity. Both can be met by capillary electrophoresis (CE), which is now regarded as a suitable technique for the diagnosis of β-thalassaemia and the detection of variant haemoglobins.

In the August issue of Pathology in Practice, the experiences of four hospital sites (Royal Hallamshire Hospital, Sheffield; Hereford County Hospital; South West London Pathology; and Birmingham Women’s Hospital) now using CE as a front-line method in the diagnosis of haemoglobinopathies will be featured, along with the advantages offered by Sebia Capillarys instruments.



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