In the fourth in the series of Pathology in Practice articles on aspects of determining measurement uncertainty (see page 19 of the November issue), Stephen MacDonald considers internal quality control (IQC), the most commonly used method to determine MU, and focuses on imprecision.
The assumptions made in this article are that the measurand has been defined, the assay has been modelled, and the assay variance as captured by IQC is the most significant contributor to what is being quantified, and is the only contributor that needs to be considered.
