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CBC-O: how haematology systems aid investigation of a raised MCHC

Modern analyser systems provide cutting-edge support to the haematology laboratory, the latest prime example of which is the benefits provided by equipment and algorithms in the investigation of the cause of a raised mean corpuscular haemoglobin concentration.

The complete blood count (CBC), also termed the full blood count (FBC), is a common test performed on automated haematology equipment to provide an evaluation of numerous aspects of the cellular components of circulating blood, namely the diagnostic parameters of white blood cells (WBCs), red blood cells (RBCs) and platelets (PLT). The interpretation and validation of FBC results and the handling of abnormal or suspicious results can prove a vital contribution to the clinical interpretation and therefore the patient diagnosis and/or treatment.1

An example of such challenging results are cases in which an elevated mean corpuscular haemoglobin concentration (MCHC) is identified, often erroneously as a result of one of many possible sample interferences. With the introduction of the CBC-O concept, Sysmex has developed a standardised method of investigating such samples. Using the XN-Series RET channel technology, CBC-O indicates the cause of an increased MCHC and offers users the most appropriate corrective actions for each specific sample, reducing the manual efforts required. With CBC-O, it is possible to report optimised CBC results for every sample – faster and with more confidence.

CBC-O (Optical): concept

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Upcoming Events

ECCMID 2024 - European Congress of Clinical Microbiology and Infectious Diseases

Fira Gran Via, 08038 Barcelona, Spain
27-30 April 2024

British Society for Microbial Technology Annual Microbiology Conference

UK Health Security Agency, Colindale, London
2 May 2024

EQA Reports: Interpreting Key Information & Troubleshooting Tips

ONLINE - Zoom
Thursday 16th May 2024

Participants’ Meeting: UK NEQAS Immunology, Immunochemistry & Allergy

Sheffield Hallam University, City Campus, Howard Street, Sheffield
24th May 2024

Med-Tech Innovation Expo

NEC, Birmingham
5-6 June, 2024

UK NEQAS Blood Coagulation: Clinical and Laboratory Haemostasis 2024

Sheffield Hallam University
5th - 6th June 2024

Access the latest issue of Pathology In Practice on your mobile device together with an archive of back issues.

Download the FREE Pathology In Practice app from your device's App store

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