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Thermo Fisher Scientific expands mass spectrometry offering

Thermo Fisher Scientific has expanded its suite of Orbitrap mass spectrometry platforms, AI-enabled software and integrated workflows, which all made their debut at the American Society for Mass Spectrometry (ASMS) Conference.

Across research, biopharma and applied testing, scientists face increasingly complex samples, expanding data sets and greater pressure to deliver confident answers faster. Thermo Fisher helps solve that challenge by bringing its flagship Orbitrap technology to more scientific decision points. The company’s expanded portfolio combines the depth of high-resolution accurate-mass technology with end-to-end solutions, enabling laboratories to advance discoveries, accelerate the development of new medicines and ensure more confident testing for food, air and water.

“Orbitrap technology has long set the standard for breakthrough discovery, and customers now want that same confidence across applied scientific markets,” said Ronald Tabaksblat, President, Chromatography and Mass Spectrometry, Thermo Fisher Scientific. “At ASMS 2026, we are showcasing how Thermo Fisher is scaling Orbitrap innovation through connected platforms, software and workflows that support advanced research, drug development and applied testing with decision-ready results.”

The new  Orbitrap Tribrid Apex mass spectrometer (pictured above, left) gives researchers a more powerful way to study challenging samples on a single platform. As Thermo Fisher’s most versatile and highest-performing Orbitrap Tribrid, the Orbitrap Tribrid Apex MS brings multiple capabilities together in one system, including three mass analysers, a new infrared laser option for alternative fragmentation and ‘Direct Mass Technology’ mode. Together, these features help researchers get clearer answers from complex biology earlier in the discovery process. Thermo Fisher also expanded its software capabilities across proteomics, spectral analysis and advanced protein characterisation:

  • MSAID and Proteinaceous, Thermo Fisher’s recent software acquisitions deliver smarter proteomics workflows that speed analysis and streamline connectivity. MSAID brings AI-driven proteomics and machine learning expertise, while Proteinaceous adds top-down and native mass spectrometry bioinformatics
  • Proteoform Studio Software provides researchers with a streamlined proteomics workflow from acquisition through reporting, including Direct Mass Technology analysis for deeper characterisation
  • Proteome Discoverer 3.4 Software helps scientists manage more proteomics workflows in one place, making it easier to analyse additional data with greater flexibility, speed and coverage.

Thermo Fisher unveiled the Orbitrap Excedion mass spectrometer (pictured, above right) an Orbitrap platform designed to reduce performance trade-offs in drug development. Built for applications ranging from drug metabolism studies to oligonucleotide and peptide analysis, the Orbitrap Excedion MS offers enhanced dynamic range (eDR) that detects three to five times more compounds in complex samples and delivers more reproducible results across larger studies. For the first time, laboratories can upgrade to Orbitrap Excedion Pro MS without replacing their instrument, which expands their analytical power while minimising cost and disruption to ongoing work.

For more information about the newest end-to-end mass spectrometry solutions, visit www.thermofisher.com/ASMS. Instruments are for general lab use only. Not for diagnostic purposes.

 

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