Biomarker testing in suspected pre-eclampsia

Hypertensive disorders, such as pre-eclampsia (PE), affect approximately 13.5% of pregnancies in the UK, which equates to around 80,000 women. Uncertainty in diagnosis of, and prognosis in, PE may lead to late diagnosis or, more frequently, unnecessary hospitalisation of women who do not go on to develop the condition. Therefore, there is an unmet medical need for short-term prediction or rule-out of the condition in pregnant women with suspected PE. A disease-specific biomarker accurately predicting maternal and neonatal complications in suspected PE cases would facilitate the decision-making of clinicians regarding monitoring and treatment.

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