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First in vitro diagnostic test to target ROS1-positive lung cancers

Roche Diagnostics has launched the VENTANA ROS1 (SP384) antibody, the first and only in vitro diagnostic ROS1 immunohistochemistry (IHC) assay. The test detects the presence of ROS1 protein in tissue, and may be useful in identifying ROS1-positive lung cancer cases. Mutations of the ROS1 gene are present in some non-small cell lung cancer (NSCLC) cases and can help indicate which patients would respond with a targeted treatment.

As these types of cancer are rare, found in up to 2% of NSCLC cases, the use of a ROS1 IHC biomarker may provide a cost-effective and efficient means of identifying cases with elevated ROS1 protein expression, before confirming by another method, such as by fluorescence in situ hybridisation (FISH) or next­generation sequencing (NGS).

“Our highly sensitive ROS1 test is the first in vitro diagnostic test available for recommended lung cancer testing guidelines, with the added benefit of rapid turnaround time,” said Pierre Hazlewood, Marketing Director at Roche Diagnostics. “While this is important in non-small cell lung cancer cases today, ROS1 is also being investigated in a number of clinical trials in other cancer types.”

www.roche.com

 

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POCT: The Power to Disrupt

The Jubilee Hotel and Conferences, Nottingham
28 March 2023

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Birmingham International Convention Centre.
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Royal Air Force Museum, Hendon, London
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4 July 2023

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25-28 September 2023

Access the latest issue of Pathology In Practice on your mobile device together with an archive of back issues.

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