Detecting carbapenem resistance using LAMP

The prevalence of carbapenem resistance is increasing on a global scale due to the lack of effective treatments, and transmission through healthcare settings into the community environment. The ability of acquired resistance to spread via vertical and horizontal gene transfer has led to sporadic global outbreaks of carbapenemase-producing organisms that are difficult to treat and expensive to manage. Incidences of previously geographically contained carbapenemases are now being observed at a growing rate in many countries as a result of modern-day travel.

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