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Risk of viruses emerging in humans may not depend on their animal host

The likelihood of emerging viruses spreading to humans from animals may not depend on the specific animal reservoir of the original virus. As in the case of the current pandemic caused by the coronavirus SARS-CoV-2, which is thought to have originated in bats, most emerging infectious diseases are zoonotic viruses – diseases that spread from animals to infect humans. As the impact of COVID-19 shows, emerging infectious diseases can seriously threaten human lives and livelihoods globally. Therefore, understanding which groups of animals or viruses pose the greatest risk is important for combating new threats.

New research, led by the MRC-University of Glasgow Centre for Virus Research, and the Institute of Biodiversity, Animal Health and Comparative Medicine at the University of Glasgow, and published in Proceedings of the National Academy of Sciences (PNAS), shows for the first time that the risk of zoonotic viruses spreading to humans is largely the same across diverse groups of animal reservoirs.

 

The study found that the proportion of viruses that are zoonotic does not significantly differ across 11 major orders of birds and mammals. It also found that the number of zoonotic viruses linked to each animal order appeared to be a consequence of species richness: more diverse animal orders hosted more viruses in general, and, by extension, more zoonotic viruses.

 

These findings suggest previous scientific thinking – that certain animal reservoirs, such as bats, pose a heightened risk of spreading viruses to humans – may not be accurate. Instead, scientists now believe that it is the characteristic traits of the viruses, rather than their animal hosts, that will be the more useful predictors of zoonotic transmission.

 

The paper ‘Viral zoonotic risk is homogenous across taxonomic orders of mammalian and avian reservoir hosts’ is published in PNAS, and was funded by Wellcome, the Royal Society and the Medical Research Council.

www.glasgow.ac.uk

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MacDonald Bath Spa Hotel, Bath
18-20 April, 2024

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The Catalyst, Newcastle upon Tyne
19 April, 2024

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Fira Gran Via, 08038 Barcelona, Spain
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UK Health Security Agency, Colindale, London
2 May 2024

EQA Reports: Interpreting Key Information & Troubleshooting Tips

ONLINE - Zoom
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Participants’ Meeting: UK NEQAS Immunology, Immunochemistry & Allergy

Sheffield Hallam University, City Campus, Howard Street, Sheffield
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