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Molecular transport medium optimised for molecular testing

PrimeStore MTM is a molecular transport medium that provides a ‘snapshot’ in time of a sample by preserving and stabilising DNA and RNA. This means that samples can be collected, transported, and processed safely and efficiently.

Millions of tubes of PrimeStore MTM have been sold to clients around the world during the SARS-CoV-2 pandemic. The molecular transport medium inactivates infectious biological pathogens including viruses, and Gram-positive/negative bacteria while preserving and stabilising labile DNA and RNA for downstream molecular applications.

PrimeStore MTM was invented and optimised specifically for molecular testing. In contrast, prior to the widespread use of molecular testing, viral transport media (VTM) were designed for transporting samples intact to be cultured, and contain ingredients that inhibit optimal molecular testing.

As the only US Food and Drug Administration (FDA) Class 2-cleared product for microbial nucleic acid storage and stabilisation, PrimeStore MTM is trusted by hospitals and laboratories to provide safer and more reliable testing than Universal Transport Medium (UTM)/VTM, saline or research use-only devices.  The key differences between PrimeStore MTM and UTM/VTM include:

  • PrimeStore MTM does not require cold chain storage and transportation
  • PrimeStore MTM inactivates the sample, along testing to take place outside of controlled containment
  • PrimeStore MTM destroys enzymes and nucleases, but preserves DNA and RNA
  • PrimeStore MTM does not inhibit PCR
  • PrimeStore MTM has a long shelf life (24 months), whereas as most UTM and VTM products can only claim six months.

Laboratories have independently validated PrimeStore MTM with a range of platforms such as Roche, Thermo Fisher, Abbott, Siemens, Luminex, Bio-Rad, PSS, Promega and bioMérieux, as well as the Cepheid GeneXpert point-of-care platform.

Another key feature of PrimeStore MTM is that it allows laboratory teams to process multiple tests from a single sample that has been inactivated and stabilised in PrimeStore MTM.  This has additional advantages for testing during the upcoming influenza season as SARS-CoV-2 and influenza can be testing on a single swab sample.

Multiple peer-reviewed scientific papers, dating from 2011 onwards, support the use of PrimeStore MTM for pathogen detection from a wide range of clinical matrices and biological fluid types collected and processed in different countries. These are available as links from the EKF Diagnostics website.

 www.ekfdiagnostics.com/PrimeStore-MTM.html

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Upcoming Events

USCAP 113th Annual Meeting

Baltimore Convention Center, Baltimore, Maryland, USA
23-28 March, 2024

Pathology Horizons 2024

MacDonald Bath Spa Hotel, Bath
18-20 April, 2024

Diagnostics North East Conference 2024

The Catalyst, Newcastle upon Tyne
19 April, 2024

ECCMID 2024 - European Congress of Clinical Microbiology and Infectious Diseases

Fira Gran Via, 08038 Barcelona, Spain
27-30 April 2024

British Society for Microbial Technology Annual Microbiology Conference

UK Health Security Agency, Colindale, London
2 May 2024

EQA Reports: Interpreting Key Information & Troubleshooting Tips

ONLINE - Zoom
Thursday 16th May 2024

Access the latest issue of Pathology In Practice on your mobile device together with an archive of back issues.

Download the FREE Pathology In Practice app from your device's App store

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