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Higher-specificity D-dimer scores in health technology assessment

Recent studies have supported a D-dimer assay role in ruling out venous thromboembolism and pulmonary embolism, linking it to health technology assessment savings, as Gillian Eyre explains.

An elevated D-dimer is now an accepted marker of a poor outcome for COVID-19 patients. Laboratory scientists played a significant part in alerting clinical colleagues on the significance of elevated D-dimer levels, not simply as a marker for the patient’s clotting risk but also the potential link between levels and outcomes.

            Of course, the main role for this specialist assay has always been in the investigation of patients with suspected venous thromboembolism (VTE) and pulmonary embolism (PE). Early diagnosis is crucial, with up to 60% of cases occurring during or within 90 days of a patient being in hospital.1 It is here that the question of cost versus benefit comes to the fore – and with it, conflicting data around the performance value of current D-dimer assays.

            In fact, Stago is one of only two global diagnostics companies that can make an exclusion claim for both DVT and PE by completely satisfying the higher Clinical and Laboratory Standards Institute (CLSI) H59-A guidelines, which the FDA has now adopted.

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Upcoming Events

Point of Care: Innovations

The Bristol - Harbourside (Doyle Collection) hotel
20 September 2022

Arab Lab Live 2022

Dubai International Convention & Exhibition Centre Dubai World Trade Centre - Trade Centre - Trade Centre 2 - Dubai - United Arab Emirates
24 - 26 October 2022

Lab Innovations 2022

Hall 2 NEC, Birmingham
2 & 3 November 2022

MEDICA 2022

Messe Düsseldorf D-40474 Düsseldorf, Stockumer Kirchstraße 61
14 - 17 November 2022

Meeting demand: the changing picture of diagnostics

The King's Fund, London, W1G 0AN
16 November 2022

Access the latest issue of Pathology In Practice on your mobile device together with an archive of back issues.

Download the FREE Pathology In Practice app from your device's App store

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