Moore M, Zahra F. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing, 2022. PMID: 34662033.
Monkeypox virus was first isolated and identified in 1958 when monkeys shipped from Singapore to a Denmark research facility fell ill. However, the first confirmed human case was in 1970 when the virus was isolated from a child in the Democratic Republic of Congo suspected to having smallpox.
Coincident immunity to monkeypox virus was previously achieved with vaccinia vaccination; however, eradicating smallpox and subsequent lack of vaccination efforts paved the way for monkeypox to gain clinical relevance. Furthermore, because most cases of monkeypox occur in rural Africa, suspected under-reporting may translate to an underestimation of the potential threat of this pathogen.
Monkeypox virus in Nigeria: infection biology, epidemiology, and evolution<