RECENT FEATURE ARTICLES

Statistical quality control:  overview of applications  in the clinical laboratory

Statistical quality control: overview of applications in the clinical laboratory

Following the recent publication of his successful articles on measurement uncertainty, Stephen MacDonald returns with the first in a new series looking at internal quality control in laboratory medicine.
Lymphoid leukaemia:  a look at the genetics  of proliferation

Lymphoid leukaemia: a look at the genetics of proliferation

Treatment of acute lymphoblastic leukaemia in children is one of the great success stories of cancer medicine. Genetic analysis continues to have a major role in the fight against this and other lymphoid leukaemias.
Nostalgia or a reality  check for the IVD industry:  a brief history of change

Nostalgia or a reality check for the IVD industry: a brief history of change

As we move through yet more amalgamation, consolidation, change – call it what you will – a time for reflection and prediction is always worthwhile. Here, Mark Reed offers a brief history of change.
Are you ready for primary molecular screening for human papillomavirus?

Are you ready for primary molecular screening for human papillomavirus?

The NHS Cervical Screening Programme is set to replace cytology screening with the molecular HPV test as the primary form of screening. Here we discuss the impact of this change and the role of a trusted partner in this process.
Next-generation IFA  testing: teaching an  old dog new tricks

Next-generation IFA testing: teaching an old dog new tricks

Jake Morrow looks at the current state of autoantibody testing, what impact this has on provision of the service, and what the future holds for this important area of autoimmunity and immunology.
Measles prevention and virus function: a brief look  in the current literature

Measles prevention and virus function: a brief look in the current literature

Figures released by Public Health England indicate that the numbers of laboratory-confirmed cases of measles increased hugely between 2017 (n=274) and the first half of 2018 (n=738). Recently published articles on the subject from around the world suggest that issues related to poor vaccination uptake and also increased immigration and the associated importation of the virus are just two of a number of reasons for this increase in infection.
Rapid diagnostics – time  is relative: a BSMT Annual  Scientific Meeting report

Rapid diagnostics – time is relative: a BSMT Annual Scientific Meeting report

Mark Wilks reports on the Annual Scientific Conference of the British Society for Microbial Technology, held at Public Health England, Colindale, London, earlier this year.
Point-of-care testing in  microbiology: an overview

Point-of-care testing in microbiology: an overview

The application of point-of-care testing has become commonplace across much of diagnostics. Here, Sarah Pitt looks at the situation in microbiology and how this technology can benefit patient care and infection control.
Translational research: designing the route from  bench to bedside

Translational research: designing the route from bench to bedside

David Martin discusses the role of architectural best practice in supporting translational research, to ensure innovations in the laboratory are transposed rapidly into successful improvements in patient outcomes.
Microbe 2018: a brief  preview of scientific and  commercial excellence

Microbe 2018: a brief preview of scientific and commercial excellence

This year’s Microbe symposium, the 17th biennial event in this series, will return to Sheffield in September. Here, Pathology in Practice provides a preview, including the vital commercial element of proceedings.
Cardiac troponins and the diagnosis of heart disease: some articles in the current literature

Cardiac troponins and the diagnosis of heart disease: some articles in the current literature

Cardiac troponin T (cTnT) and troponin I (cTnI) are cardiac regulatory proteins that control the calcium-mediated interaction between actin and myosin. Raised cardiac troponin concentrations are now accepted as the standard biochemical marker for the diagnosis of myocardial infarction.
Optimising Mohs clinic  flow and patient treatment: the vital role of cryotomy

Optimising Mohs clinic flow and patient treatment: the vital role of cryotomy

The University Hospital of Wales, Cardiff, has pioneered Mohs micrographic surgery since 1992, providing optimal patient care and rapid skin cancer treatment. Central to fast treatment time is cryosectioning, which is facilitated by use of the Thermo Scientific Cryostar NX70.
UK NEQAS: coordinating  point-of-care testing

UK NEQAS: coordinating point-of-care testing

Point-of-care testing is vitally important in many areas of 21st-century healthcare, and requires medical laboratory overview to ensure a safe an efficient service. External quality assessment is an important aspect of this assurance, as this report illustrates.
Storage, archiving and  retrieval of bacteria and  fungi: overview and update

Storage, archiving and retrieval of bacteria and fungi: overview and update

Biobanking increases in importance as scientific development and research continues. Here, Mark Reed offers a brief, not on the high street, insight into what is now a complex science.
Serological infectious  diseases: a solution that  meets a gap in the market

Serological infectious diseases: a solution that meets a gap in the market

Jamie Laughlin explores the benefits of a novel, innovative solution for serological infectious diseases testing recently introduced at South West London Pathology, part of St George’s University Hospitals NHS Foundation Trust.
Assay to assess bleeding  risk in haemophilia A and B  patients: a case study

Assay to assess bleeding risk in haemophilia A and B patients: a case study

A coagulation laboratory in Cambridge is part of a pan-European study looking at the in vitro diagnostics potential for automated thrombin generation testing in the routine laboratory setting.
Forward-thinking software and instrumentation transform NHS pathology services

Forward-thinking software and instrumentation transform NHS pathology services

The need to share, analyse and compare data across numerous laboratories is becoming more relevant as plans for larger NHS pathology networks unfold. Here, North West London Pathology and Stago illustrate how this can be facilitated.
Putting it all together, building the measurement uncertainty budget

Putting it all together, building the measurement uncertainty budget

The seventh and final article in this series by Stephen MacDonald on individual aspects of the assessment of uncertainty of measurement provides an example of how to set, assess and review measurement uncertainty in any situation in the laboratory.
Rapid diagnosis of toxigenic Clostridium difficile using a novel LAMP technology

Rapid diagnosis of toxigenic Clostridium difficile using a novel LAMP technology

The identification of C. difficile carriers who have the potential to produce toxin can take up to four days, delaying patient isolation and increasing the chance of nosocomial spread of infection. Here, Laura Nottle considers the performance and benefits of a tcdB gene detection assay.
Loop-mediated isothermal amplification: diagnostics closer to the patient

Loop-mediated isothermal amplification: diagnostics closer to the patient

The development of new nucleic acid amplification techniques is bringing molecular diagnostics closer to the patient for faster results and improved patient management. A prime example of this near-patient capability is LAMP technology.

Upcoming Events

IBMS Biomedical Science Congress

ICC, Birmingham
22-25 September 2019

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30 & 31 October 2019

The genomic and molecular revolution in microbiology: in technology we trust (or do we?).

RAF Museum, Hendon, London
14 May 2020

Clinical and Laboratory Haemostasis 2020

STEM/Atrium Conference Centre, Sheffield Hallam University
3-4 June 2020

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