RECENT FEATURE ARTICLES

Testing for oestradiol is a crucial first step in the time-sensitive IVF process. Detailed here are the steps a French-based laboratory was able to take to automate this previously time-consuming and labour-intensive task safely and effectively, while still meeting important deadlines.

Current challenges within sepsis diagnostics and AMR show the need for a standardised blood culture pathway. Stefan Schraag explores how the med tech industry can support this through greater education and innovation. This article follows on from a stakeholder event taking a holistic view of the blood culture pathway and encouraging diagnostic integration beyond the walls of laboratories.

Relics of ancient viruses, endogenous retroviruses that can be found in human DNA, have recently found exposure in the media. But what range of applications can be found in the recent literature? Here, Pathology in Practice Science Editor Brian Nation compiles a small selection of current research interest in the field.

In the second of two articles for Pathology in Practice, retired biomedical scientist David Norcliffe, with David Manuel, looks at how clinical viscosity testing can be used more widely, with the measurement of viscosity having a considerable number of possible applications which are receiving further investigation.

The biennial IBMS Congress will return to the International Convention Centre in Birmingham in September, the focus once again being on the very best that biomedical science and commercial colleagues have to offer. Here, Pathology in Practice provides a further brief preview of the four-day event.

In order to cope with the challenges of the future, it is critical to optimise diagnostic services and enable faster and earlier testing. Here, Tracey Sainsbury discusses the key challenges and opportunities that lay ahead for this vital area of healthcare.

With laboratories turning to technology and automation to meet the challenges of rising workloads and shrinking budgets, equipment supplier BD has recently created its Integrated Diagnostic Solutions (IDS) division, which has consolidated the firm’s workflow optimisation services. Here, BD Professional Services explains how this is being achieved and the laboratory staff at Liverpool Clinical Laboratories share their experiences.

Developments in lateral-flow assay technology have been highlighted by its ubiquitous use during the SARS-CoV-2 pandemic, but its utility covers a much wider spectrum of applications. Here, Pathology in Practice Science Editor Brian Nation compiles a small selection of current research activity in the field.

In just a few months the biennial IBMS Congress will return to the International Convention Centre in Birmingham. The focus once again will be on the very best that biomedical science and those supporting the scientific programme have to offer. To illustrate this, Pathology in Practice focuses on a small selection of topics and their respective speaker biographies.

Graham Johnson discusses how gastroenterology has changed over the past 20 years. He looks at how non-invasive diagnostic testing, prior to endoscopy, could provide a solution to earlier detection and better outcomes for upper gastrointestinal disorders.

With antimicrobial resistance continuing to be a huge global health issue, lateral flow tests that can detect resistance markers are emerging as a simple, economic and rapid alternative to existing methods of detecting antibiotic resistance. With their comparable performance to molecular methods, Naomi Chant of Una Health explains how these tests are changing the landscape of AMR detection in routine microbiology laboratories.

In part one of a two-part series David Norcliffe presents a study of clinical viscosity, outlining how it is measured and how it is used as part of the diagnosis of various conditions. Part two – to run in the next issue – looks at future applications of this technology.

This year’s British Society for Microbial Technology Annual Microbiology Conference will be held on 11 May at the RAF Museum in Hendon, North London. Here, BSMT Chair Dr Mark Wilks continues his preview of the programme and introduces two more themes of the meeting.

Initially a digital sceptic, being introduced to digital pathology technology and methods has ignited a new passion for Dr Azzam Ismail, a Consultant Neuropathologist, Leeds Teaching Hospitals. Here, he tells Pathology in Practice how his working life has changed.

In the risk assessment of point-of-care services, the aim is to provide a robust service that provides the right result on the right patient every time. Here, Carole Gough looks not only to standards in the laboratory, but also to international risk management standards applicable across, for example, the pharmaceutical, medical device and aviation industries.

A new method to detect Clostridioides difficile can yield accurate results in as little as 15 minutes, leading to faster clinical decision-making and improving case management. Here, Jürgen Becker describes how this innovative assay can be integrated into near-patient testing, and outlines the positive impact it could have on hospital workflows and patient care.

Starting a new series of articles on the changing state of regulation for medical devices and in vitro diagnostic equipment, Ashleigh Batchen, Head of Regulatory Affairs at BIVDA (the British In Vitro Diagnostics Association) writes for Pathology in Practice looking at the current situation and forthcoming changes as a result of Brexit.

The potential benefits to personalised medicine likely to be offered in the near future by genomics are huge. But to start realising them, laboratories need to overcome the challenge of ‘big data’ which could stop them embracing these new technologies, says Emma Huntridge of Clinisys.

Specialist biomedical scientist Rakhee Surti details a recent project to evaluate community POCT services around Milton Keynes, initiated to document key strategic recommendations for improving and digitally transforming POCT services within the primary care community.

The North East Innovation Lab is celebrating its second anniversary having expanded its work in accelerating the development of diagnostics across a wide range of applications. Pathology in Practice hears from the laboratory about recent changes and the important role it has played in a number of high-profile projects.