Beckman Coulter has introduced two new IOTest reagents, Anti-NTB-A-PE and CD226 (DNAM-1)-PE. Both are monoclonal antibodies to cell surface receptors for natural killer (NK) cell studies, which provide important information in disease research. These new flow cytometry reagents are compatible with Beckman CoulterÆs FC 500 series and Cell Lab Quanta SC systems, as well as with other instrument platforms.
Activating NK receptors detect surface molecules that are upregulated in virus-infected and tumour cells but powerless in normal cells.
The IOTest Anti-NTB-A-PE reacts with the signalling lymphocyte activation molecule, which is a member of a newly discovered family of NK receptors called SLAM. These are important functional receptors in lymphocytes and other leucocytes.
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