Synbiosis has introduced its next-generation Ames software module featuring a time-saving Ames mutagenicity ratio calculation function. The new software designed for integrated use with the ProtoCOL 3 colony counter, facilitates rapid production of accurate, consistent count and ratio data from Ames test plates and is ideal for use in regulated toxicology testing laboratories.
The new Ames software enables ProtoCOL 3 to quickly count Salmonella typhimurium or Escherichia coli colonies cultured on, for example, Vogel Bonner medium before and after exposure to potentially toxic or non-toxic control compounds. The software can then automatically compare the different colony counts to generate an Ames mutagenicity ratio, providing a quick guide to the mutagenic potential of a test chemical. This saves microbiologists time and effort with transferring count data to statistical software or manually calculating the ratio.
As well as numerical data, the software also produces full colour images of Ames test plates, which can be stored in a secure SQL database for reference and another count, if required. Count and ratio data can be automatically downloaded to a spreadsheet (Excel/OpenOffice) or LIMS, thus eliminating data transfer errors, to generate reproducible, traceable results, which are consistent from one microbiologist to another.