Recent press coverage of COVID-19 disease has highlighted a possible role for interleukin-7 in boosting T-cell numbers and aiding recovery. However, the current literature reports on a wide range of other benefits of this important cytokine.
Interleukin-7 protects against bacterial respiratory infection by promoting IL-17A-producing innate T-cell response
Hassane M, Jouan Y, Creusat F et al. Mucosal Immunol 2020 Jan; 13 (1): 128–39. doi: 10.1038/s41385-019-0212-y.
Interleukin-7 (IL-7) is a critical cytokine in B- and T-lymphocyte development and maturation. Recent evidence suggests that IL-7 is a preferential homeostatic and survival factor for RORγt+ innate T cells such as natural killer T (NKT) cells, γδT cells, and mucosal-associated invariant T (MAIT) cells in the periphery.
Log in or register FREE to read the rest
This story is Premium Content and is only available to registered users. Please log in at the top of the page to view the full text.
If you don't already have an account, please register with us completely free of charge.