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Early diagnosis of HPV16 cancers: novel assay offers high specificity

The incidence of virus-related head and neck tumours is reaching epidemic proportions, particularly in the developed world. Anna Huber provides an overview and discusses the need to improve patient outcomes.

A breakthrough in the detection of cancers caused by human papillomavirus (HPV) is on the horizon with the launch of the Abviris HPV16 subtype-specific serological assay. Unlike the more common molecular methods for the detection of HPV DNA in cells and tissues, the test relies on detecting an immune response that occurs when an HPV infection has led to tumour growth.

                Experts have been warning of a ‘virus-related cancer epidemic’ and calling for improved methods of early detection, treatment control and post-treatment surveillance of HPV-induced cancers.1 At the same time, they stress that any solution must be cost-effective and easy to integrate into clinical practice.

                Healthcare agencies worldwide view HPV vaccination as the silver bullet against HPV cancers. However, vaccinated populations will not reach cancer-relevant age for many decades and there are still over seven billion individuals currently unprotected.2 As a result, incidence of HPV-induced cancer will continue to rise, alongside a rise in the need to expand detection strategies beyond cervical cancer.

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Upcoming Events

ECCMID 2024 - European Congress of Clinical Microbiology and Infectious Diseases

Fira Gran Via, 08038 Barcelona, Spain
27-30 April 2024

British Society for Microbial Technology Annual Microbiology Conference

UK Health Security Agency, Colindale, London
2 May 2024

EQA Reports: Interpreting Key Information & Troubleshooting Tips

ONLINE - Zoom
Thursday 16th May 2024

Participants’ Meeting: UK NEQAS Immunology, Immunochemistry & Allergy

Sheffield Hallam University, City Campus, Howard Street, Sheffield
24th May 2024

Med-Tech Innovation Expo

NEC, Birmingham
5-6 June, 2024

UK NEQAS Blood Coagulation: Clinical and Laboratory Haemostasis 2024

Sheffield Hallam University
5th - 6th June 2024

Access the latest issue of Pathology In Practice on your mobile device together with an archive of back issues.

Download the FREE Pathology In Practice app from your device's App store

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