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App to help demystify the effect of SARS-CoV-2 mutations

The SARS-CoV-2 pandemic has focused everyone’s attention on the hidden world of viruses. The emergence of new variants, such as Beta and Delta, affects everyone: some variants spread more quickly and some are less affected by vaccines. But why?

Teams of scientists around the world, including the COVID-19 Genomics UK (COG-UK) consortium, are tracking the emergence of new variants of SARS-CoV-2, but to understand why the mutations they report have the effects they do requires an expert understanding of the details of how SARS-CoV-2 functions.  

In response to this Sarah Iannucci, an MSc in Medical Visualisation and Human Anatomy at The Glasgow School of Art (School of Simulation and Visualisation) and University of Glasgow (School of Life Sciences), set out to explain the hidden workings of SARS-CoV-2 and its variants, particularly those on the viral spike protein.

Sarah built the SARS-CoV-2 Spike Mutation Explorer, an interactive web application using illustration, animation and interactive 3D models to explain why SARS-CoV-2 mutations have the effects they do, with users able to view and interact with visualisations of variants of concern and their characteristic mutations. The work was unveiled on 9 September as part of The Glasgow School of Art’s Postgraduate Showcase.

The SARS-CoV-2 Spike Mutation Explorer was developed in collaboration with COG-UK, and with it Sarah aims to provide the context needed for non-experts such as the media to understand the technical reports on SARS-CoV-2 variants presented in the COG-UK website and then share them with the wider public.

www.glasgow.ac.uk

 

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Upcoming Events

analytica 2022

Messe München, Germany
June 21-24, 2022

The Genomic and Microbiology Revolution: In Technology We Trust?

Royal Air Force Museum, Hendon, London
19 July 2022

Arab Lab Live 2022

Dubai International Convention & Exhibition Centre Dubai World Trade Centre - Trade Centre - Trade Centre 2 - Dubai - United Arab Emirates
24 - 26 October 2022

Lab Innovations 2022

Hall 2 NEC, Birmingham
2 & 3 November 2022

MEDICA 2022

Messe Düsseldorf D-40474 Düsseldorf, Stockumer Kirchstraße 61
14 - 17 November 2022

Access the latest issue of Pathology In Practice on your mobile device together with an archive of back issues.

Download the FREE Pathology In Practice app from your device's App store

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