Relics of ancient viruses, endogenous retroviruses that can be found in human DNA, have recently found exposure in the media. But what range of applications can be found in the recent literature? Here, Pathology in Practice Science Editor Brian Nation compiles a small selection of current research interest in the field.
Resurrection of endogenous retroviruses during aging reinforces senescence
Liu X, Liu Z, Wu Z et al. Cell. 2023 Jan 19; 186 (2): 287–304.e26. doi: 10.1016/j.cell.2022.12.017.
Whether and how certain transposable elements with viral origins, such as endogenous retroviruses (ERVs) dormant in our genomes, can become awakened and contribute to the ageing process is largely unknown.
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