In a post-pandemic world, it is perhaps counter-intuitive to suggest that viral agents could contribute to medicine’s fight against the rise of antimicrobial resistance. However, the use of bacteriophages against bacterial infection predates the antibiotic era, so what are some of the opportunities currently being explored? Here, Pathology in Practice Science Editor Brian Nation compiles a small selection of recent research interest.
Phage therapy for antibiotic-resistant bacterial infections
Hatfull GF, Dedrick RM, Schooley RT.
Annu Rev Med. 2022 Jan 27; 73: 197–211. doi: 10.1146/annurev-med-080219-122208.
Antibiotic resistance in bacterial pathogens presents a substantial threat to the control of infectious diseases. Development of new classes of antibiotics has slowed in recent years due to pressures of cost and market profitability, and there is a strong need for new antimicrobial therapies.
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