FEATURE ARTICLES
Prion diseases: a brief look in the current literature
Prion diseases or transmissible spongiform encephalopathies are a family of rare progressive neurodegenerative disorders that affect both humans and animals. A recent confirmed case of bovine spongiform encephalopathy in Scotland has brought this devastating group of diseases, that are usually rapidly progressive and always fatal, back into focus.
Serious Hazards of Transfusion scheme: a review of 2017 data
Laboratory incidents specialist Hema Mistry summarises the 2017 SHOT Annual Report, and looks at why the same errors continue to occur and how many of them could have been prevented.
Calprotectin and elastase: update on faecal testing for gastrointestinal diseases
Screening of faecal samples for blood and microorganisms is commonplace, yet testing that can distinguish irritable from inflammatory bowel conditions, and detect pancreatic exocrine insufficiency. is equally important, as this review illustrates.
Clinical and Laboratory Haemostasis 2018: a UK NEQAS BC update
Tim Woods collates abstracts that reflect proceedings of the UK NEQAS for Blood Coagulation annual scientific and participants’ two-day meeting, which was held in Sheffield earlier in the year.
Tuberculosis: a view of bioinformatics, molecular typing and spoligotyping
Over the past decade, much research effort has been invested in the genomics and epidemiology of Mycobacterium tuberculosis infection, one of the world’s deadliest diseases. Currently, scientific and political initiatives aim to improve the situation.
Statistical quality control: overview of applications in the clinical laboratory
Following the recent publication of his successful articles on measurement uncertainty, Stephen MacDonald returns with the first in a new series looking at internal quality control in laboratory medicine.
Lymphoid leukaemia: a look at the genetics of proliferation
Treatment of acute lymphoblastic leukaemia in children is one of the great success stories of cancer medicine. Genetic analysis continues to have a major role in the fight against this and other lymphoid leukaemias.
Nostalgia or a reality check for the IVD industry: a brief history of change
As we move through yet more amalgamation, consolidation, change – call it what you will – a time for reflection and prediction is always worthwhile. Here, Mark Reed offers a brief history of change.
Are you ready for primary molecular screening for human papillomavirus?
The NHS Cervical Screening Programme is set to replace cytology screening with the molecular HPV test as the primary form of screening. Here we discuss the impact of this change and the role of a trusted partner in this process.
Next-generation IFA testing: teaching an old dog new tricks
Jake Morrow looks at the current state of autoantibody testing, what impact this has on provision of the service, and what the future holds for this important area of autoimmunity and immunology.
Measles prevention and virus function: a brief look in the current literature
Figures released by Public Health England indicate that the numbers of laboratory-confirmed cases of measles increased hugely between 2017 (n=274) and the first half of 2018 (n=738). Recently published articles on the subject from around the world suggest that issues related to poor vaccination uptake and also increased immigration and the associated importation of the virus are just two of a number of reasons for this increase in infection.
Rapid diagnostics – time is relative: a BSMT Annual Scientific Meeting report
Mark Wilks reports on the Annual Scientific Conference of the British Society for Microbial Technology, held at Public Health England, Colindale, London, earlier this year.
Point-of-care testing in microbiology: an overview
The application of point-of-care testing has become commonplace across much of diagnostics. Here, Sarah Pitt looks at the situation in microbiology and how this technology can benefit patient care and infection control.
Translational research: designing the route from bench to bedside
David Martin discusses the role of architectural best practice in supporting translational research, to ensure innovations in the laboratory are transposed rapidly into successful improvements in patient outcomes.
Microbe 2018: a brief preview of scientific and commercial excellence
This year’s Microbe symposium, the 17th biennial event in this series, will return to Sheffield in September. Here, Pathology in Practice provides a preview, including the vital commercial element of proceedings.
Cardiac troponins and the diagnosis of heart disease: some articles in the current literature
Cardiac troponin T (cTnT) and troponin I (cTnI) are cardiac regulatory proteins that control the calcium-mediated interaction between actin and myosin. Raised cardiac troponin concentrations are now accepted as the standard biochemical marker for the diagnosis of myocardial infarction.
Optimising Mohs clinic flow and patient treatment: the vital role of cryotomy
The University Hospital of Wales, Cardiff, has pioneered Mohs micrographic surgery since 1992, providing optimal patient care and rapid skin cancer treatment. Central to fast treatment time is cryosectioning, which is facilitated by use of the Thermo Scientific Cryostar NX70.
UK NEQAS: coordinating point-of-care testing
Point-of-care testing is vitally important in many areas of 21st-century healthcare, and requires medical laboratory overview to ensure a safe an efficient service. External quality assessment is an important aspect of this assurance, as this report illustrates.
Storage, archiving and retrieval of bacteria and fungi: overview and update
Biobanking increases in importance as scientific development and research continues. Here, Mark Reed offers a brief, not on the high street, insight into what is now a complex science.
Serological infectious diseases: a solution that meets a gap in the market
Jamie Laughlin explores the benefits of a novel, innovative solution for serological infectious diseases testing recently introduced at South West London Pathology, part of St George’s University Hospitals NHS Foundation Trust.
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BSMT 40th Anniversary Microbiology Conference
RAF Museum, Hendon, London NW9 5LL
15 May, 2025
Transforming Digital Pathology & AI: The Path Forward
Royal College Of Physicians Of Edinburgh
15 May, 2025
The 10 Year Plan - Clinical Innovations Expo
Jubilee Hotel and Conference Centre, Nottingham, UK
15 May, 2025
Incorrect Blood Component Transfused: a SHOT webinar
Online
21 May 2025
Near miss reporting and WBIT: a SHOT webinar
Online
9 June 2025