RECENT NEWS

Researchers have generated the first immortalised cell lines that allow more-efficient manufacture of red blood cells. The results, published in Nature Communications (Trakarnsanga K, Griffiths RE, Wilson MC et al. An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells. Nat Commun 2017 Mar 14; 8: 14750. doi: 10.1038/ncomms14750) could, if successfully tested in clinical trials, lead to a safe source of transfusions for people with rare blood types, and in areas of the world where blood supplies are inadequate or unsafe.

Professor Andrew Morris has been appointed director of the new UK health and biomedical informatics research institute, which is to be named Health Data Research UK (HDR UK). The new institute will, for the first time, incorporate on a national scale the entire breadth of data science research aimed at improving human health.

Ranjit Rai is probably the longest serving and most widely travelled laboratory autoclave service engineer working out of Britain. He joined Priorclave within months of its formation, building autoclaves before becoming the company’s only service engineer providing customer support across the UK. Shortly after his appointment as service manager, Ranjit celebrated 25 years with the company.

It lives inside one-third of the UK population and is a common infection in cats; however, scientists previously knew little about how the Toxoplasma parasite communicated with its host. Now, new research by the University of Glasgow’s Wellcome Centre for Molecular Parasitology, in collaboration with The University of Vermont, has revealed how the parasite uses a key protein to form a communication network and ultimately continue the infection process.

A recent time and motion study by University Hospital Southampton NHS Foundation Trust has demonstrated a 1.5 minute (>20%) reduction in time to blood gas results when using the Proxima bedside blood gas monitoring system from Sphere Medical. The results were presented at the British Association of Critical Care Nurses conference and Intensive Care Society State of the Art meeting as a scientific poster.

An educational board game to help improve team performance in health and social care organisations has been developed by Focus Games in collaboration with NHS Lothian.

Arquer Diagnostics, the developer of a high-sensitivity, high-specificity, enzyme-linked immunosorbent assay (ELISA)-based urine test for bladder cancer, has recruited 801 patients for a clinical trial to evaluate the company’s MCM5 bladder cancer diagnostics test. The results from the study will be used as part of the company’s application for CE mark approval, ahead of the commercial launch of the MCM5 ELISA planned for later in the year.

Globally recognised as a symbol of design excellence, the iF design awards celebrate the best in user-focused, ergonomic and efficient design. With over 5000 submissions from 70 countries, Olympus Scientific Solutions has received two of these prestigious awards for its CX23 upright microscope and FLUOVIEW FV3000 confocal laser scanning microscope.

The rise of antibiotic resistance is at the heart of a new BBC drama, written by Val McDermid and shaped by scientific expertise from the University of Warwick. Airing on BBC Radio 4 this month (3, 10 and 17 March, 2.15 pm), Resistance is a three-part story about an epidemic of a drug-resistant disease.

The National Cancer Institute (NCI), the National Institutes of Health (NIH), American Society for Clinical Pathology (ASCP), Sakura Finetek and other partners have opened a state-of-the-art histopathology laboratory in Butaro, Rwanda, providing patients in resource-limited areas of the country with access to rapid cancer diagnostics and appropriate care and treatment.

The Cancer Research Technology (CRT) Pioneer Fund has invested in the development of a promising new class of drugs for blood cancer. The funding will support Cancer Research UK scientists at The Institute of Cancer Research, London, who are designing the drugs, to treat patients with diffuse large B‐cell lymphoma (pictured), a subtype of non‐Hodgkin’s lymphoma.

Researchers at The Institute of Cancer Research (ICR), London, are taking advantage of the single-cell encapsulation capabilities of Dolomite Bio’s Single Cell RNASeq system to investigate resistance mechanisms in prostate cancer. Karolina Nowakowska, a PhD student at ICR, explained: “Our team is focused on studying treatment resistance in prostate cancer patients, looking at the biochemical mechanisms responsible. My project is based on using single-cell sequencing to help identify the specific genes which lead to treatment resistance, trying to identify biomarkers and, in the longer term, treatments that will allow a more personalised approach to therapy.”

Researchers from the Harold C Simmons Comprehensive Cancer Center at UT Southwestern Medical Center have found that high expression of a gene called SHOX2 predicts poor survival in intermediate grade gliomas. This potential biomarker for glioma, a common type of brain cancer, could help clinicians determine how aggressive a cancer is, and help to determine the best course of treatment.

The shape of bacteria does not influence how well they can move. This is the surprising finding of new research which could have major implications for the future of the scientific and medical industries. Published in Nature’s new Ecology & Evolution journal, the results refute long-held theories that there should be a strong link between the evolution of shape in bacteria and their ability to move.

Beckman Coulter has appointed Ed Harris as its new product manager for IT in Northern Europe. As a product expert with a passion for healthcare and a vision of the benefits that IT can bring to patient outcomes through enhanced efficiencies, Ed is responsible for overseeing Beckman Coulter’s clinical information systems portfolio. He will also drive the company’s IT strategy and product innovation in order to advance healthcare for all stakeholders. In particular, he will ensure the effective support of clinical laboratory managers in their drive for efficiency and quality.

Recently, pathologists and laboratory scientists came together to celebrate another National Pathology Week (NPW), during which they staged events to increase awareness and improve the public understanding of pathology.

Test equipment specialist Testo has supplied its Saveris 2 temperature and humidity data logging system to Stansted Laboratories’ facility in Barking, East London. Stansted Laboratories is a UKAS-accredited laboratory of 20 staff analysing over 50,000 samples a year in a purpose built facility. It specialises in microbiological analysis of water and air, and especially Legionella testing of water and drinking water bacteriological analysis.

Approximately 41,000 people are diagnosed with colorectal cancer (CRC) in the UK each year, and over 90% of cases are treated successfully following early detection. However, to selectively refer those patients with suspected CRC in a primary care setting remains immensely challenging. The recent revision of the National Institute for Health and Care Excellence (NICE) NG12 ‘red flag’ criteria for the two-week wait aims to increase the CRC detection rate.

Researchers have found a group of circulating tumour cells in prostate cancer patient blood samples which are linked to the spread of the disease, according to new research presented at the National Cancer Research Institute (NCRI) Cancer Conference in Liverpool. This is the first time that these cell types have been shown to be a promising marker for prostate cancer spread

Scientists have discovered a new way to replicate the regenerative power of stem cells in the laboratory, which could lead to powerful treatments for injuries and diseases. In a paper published in the journal ACS Nano, Dr Catherine Berry and Professor Matthew Dalby from the University of Glasgow’s Institute of Molecular Cell and Systems Biology, describe how they have been able create and control bundles of bone marrow stem cells that act as the stem cells do in the body. These bundles of cells are capable of healing injuries in laboratory‐grown bone and cartilage models.